We recently had a technology conference at our service center and one of the sessions was on games in the classroom (both online & board games). These were very subject specific for social studies & language arts. I honestly haven't played these games. So, these aren't my recommendations, just games that I saw in a demo. Look online to find reviews.
Once Upon a Time - a creative storytelling card game by Atlas games. Students draw cards to add settings, characters, quotations, and plot twists to a story.
Days of Wonder - www.daysofwonder.com/ - and Rio Grande Games - www.riograndegames.com/ - both offer many games related to geography or historical time periods Some of them include "Ticket to Ride" - build a railroad across the U.S.; "Carcassonne: Hunters & Gatherers" - build a pre-historic community; and "Metropolys" - create your own city.
GMT Games - also has games on historical themes, such as "Blackbeard - The Golden Age of Piracy" Students take on the role of one or more pirates.